ECOLAB > Pages profils > MOUCHET Florence

Profil de Florence MOUCHET

Email : florence.mouchetSPAMFILTER@ensat.fr

Téléphone / phone: 05 34 32 39 36

Bureau / office : 1247

Institution : CNRS

Statut / status: ITA

Adresse professionnelle / address:

ECOLAB UMR CNRS 5245
Integrative Ecotoxicology team
Site ENSAT
Avenue de l'Agrobiopole
BP 32 607
31326 AUZEVILLE TOLOSANE Cedex

Site perso / personal website :

Main/Recent publications

Revues internationales à comité de lecture

1. Devillers J, Chezeau A, Thybaud E, Poulsen V, Graff L, Vasseur P, Chenon P, Mouchet F, Ferrier V, Quiniou F. 2002. Ecotoxicity of ethylene glycol monomethyl ether and its acetate.Toxicol. Mech. Method. 12: 241-254.

2. Devillers J, Chezeau A, Thybaud E, Poulsen V, Porcher M, Graff L, Vasseur P, Mouchet F, Ferrier V, Quiniou F. 2002. Ecotoxicity of ethylene glycol monobutyl ether and its acetate.Toxicol. Mech. Method. 12: 255-263.

3. Gauthier L, Tardy E, Mouchet F, Marty J. 2004. Biomonitoring of the genotoxic potential (micronucleus assay) and detoxifying activity (EROD induction) in the river Dadou-France, using the amphibian Xenopus laevis. Sci. Total Environ. 323(1-3): 47-61.

4. Mouchet F, Gauthier L, Mailhes C, Ferrier V, Devaux A. 2005. Comparative Study of the Comet Assay and the Micronucleus Test in Amphibian Larvae (Xenopus laevis) Using Benzo(a)pyrene, Ethyl Methanesulfonate, and Methyl Methanesulfonate: Establishment of a Positive Control in the Amphibian Comet Assay. Environ. Toxicol. 20(1): 74 - 84.

5. Mouchet F, Gauthier L Mailhes C, Jourdain MJ, Ferrier V, Devaux A. 2005. Biomonotoring of the genotoxic potential of draining water from dredged sediments, using the comet and micronucleus tests on amphibian (Xenopus laevis)and bacterial assays (Mutatox® and Ames tests).J. Toxicol. Env. Health A, 68(10): 811-832.

6. Mouchet F, Gauthier L, Mailhes C, Jourdain MJ, Ferrier V, Triffault G, Devaux A. 2006. Biomonitoring of the genotoxic potential of aqueous extracts of soils and bottom ash resulting from municipal solid waste incineration, using the comet and micronucleus tests on amphibian (Xenopus laevis) larvae and bacterial assays (Mutatox® and Ames tests).Sci. Total Env. 355 (1-3): 232-246.

7. Mouchet F, Gauthier L, Mailhes C, Ferrier V, Devaux A. 2006. Comparative evaluation of the genotoxicity of captan in amphibian larvae (Xenopus laevis and Pleurodeles waltl) using the comet assay and the micronucleus test. Environ. Toxicol. 21(3): 264-77.

8. Mouchet F, Baudrimont M, Gonzalez P, Cuenot Y, Bourdineaud JP, Boudou A, Gauthier L. 2006. Genotoxic and stress inductive potential of cadmium inXenopus laevis larvae. Aquat. Toxicol. 78(2): 157-166.

9. Deydier E, Guilet R, Cren S, Pereas V, Mouchet F, Gauthier L. 2006. Evaluation of meat and bone meal combustion residue as lead immobilizing material for in-situ remediation of polluted aqueous solutions and soils: Chemical and ecotoxicological studies. J.Hazard. Mater. 146: 227-236. 

10. Mouchet F, Cren S, Cunienq C,  Deydier E, Guilet R, Gauthier L. 2007. Assessment of lead ecotoxicity in water using the amphibian larvae (Xenopus laevis) and preliminary study of its immobilization in meat and bone meal combustion residues. Biometals, 20(2): 113-127.

11. Mouchet F, Gauthier L, Baudrimont M, GonzalezP, Mailhes C, Ferrier V, Devaux A. 2007. Comparative evaluation of the toxicity and genotoxicity of cadmium in amphibian larvae (Xenopus laevis and Pleurodeles waltl) using the comet assay and the micronucleus test. Environ. Toxicol. DOI 10.1002/tox : 422-435.

12. Mouchet F, Landois P, Flahaut E, Pinelli E, Gauthier L. 2007. Assessment of the potential in vivo ecotoxicity of Double-Walled Carbon Nanotubes (DWNTs) in water, using the amphibian Ambystoma mexicanum. Nanotoxicology, 1(2): 149 – 156.

13. Mouchet F, Cren S, Deydier E, Guilet R, Gauthier L. 2008. Preliminary study of Lead (Pb) immobilization by meat and bone meal combustion residues (MBMCR) in soil: Assessment of Pb toxicity (phytotoxicity and genotoxicity) using the tobacco model (Nicotiana tabacum var.xanthi Dulieu). Biometals 21(4): 443-58.

14. Mouchet F, Landois P, Sarremejean E, Bernard G, Puech P, Pinelli E, Flahaut E, Gauthier L. 2008. Characterisation andin vivoecotoxicity evaluation of double walled carbon nanotubes in larvae of the amphibian Xenopus laevis. Aquat Toxicol 87: 127-137.

15. Coutand M, Deydier E, Cyr M, Mouchet F, Gauthier L, Guilet R, Bernues Savaete L, Cren S, Clastres P. 2009. Evaluation of laboratory and industrial meat and bone meal combustion residue as cadmium immobilizing material for in-situ remediation of polluted aqueous solutions: “Chemical and ecotoxicological studies”. J.Hazard. Mater. 166(2-3): 945-953. doi:10.1016/j.jhazmat.2008.11.104.

16.Marquis O, Miaud C, Ficetola F, Bocher A, Mouchet F, Guittonneau S, Devaux A. 2009.Variation in genotoxic stress tolerance among frog populations exposed to UV and pollutant gradients. Aquat Toxicol 95(2):152-61.

17. Mouchet F, Landois P, Datsyuk V, Puech P, Pinelli E, Flahaut E, Gauthier L. 2011. International amphibian micronucleus standardized procedure (ISO 21427-1) for in vivo evaluation of double-walled carbon nanotubes toxicity and genotoxicity in water. Environ Toxicol. 26(2):136-45.doi: 10.1002/tox.20537.

18. Mouchet F, Landois P, Puech P, Pinelli E, Flahaut E, Gauthier L. 2010. CNT ecotoxicity in amphibians:  assessment of Multi Walled Carbon Nanotubes (MWNT) and Comparison with Double Walled Carbon Nanotubes (DWNT). Special focus Environmental Toxicity of Nanoparticles. Nanomedicine 5(6): 963–974.

19. Bourdiol F, Mouchet F,Perrault A, Fourquaux I, Datas L, Gancet C, Boutonnet JC, Pinelli E, Gauthier, Flahaut E. 2012. Biocompatible polymer-assisted dispersion of multi walled carbon nanotubes in water, application to the investigation of their ecotoxicity usingXenopus laevisamphibian larvae. Carbon. 54 : 175-191.

20. Sánchez-Pérez JM, Montuelle B, Mouchet F, Gauthier L, Julien F, Sauvage S, Teissier S, Dedieu K, Destrieux D, Vervier P, Gerino M. 2013. Role of the hyporheic heterotrophic biofilm on transformation and toxicity of pesticides. Ann. Limnol. - Int. J. Lim. 49(02): 87-95.

21. Saria R, Mouchet F, Perrault A, Flahaut E, Laplanche C, Boutonnet JC, Pinelli E, Gauthier L. 2014. Short term exposure to multi-walled carbon nanotubes induce oxidative stress and DNA damage in Xenopus laevis tadpoles. Ecotoxicol Env Safety. 107: 22-29. DOI: http://dx.doi.org/10.1016/j.ecoenv.2014.05.010.

22. Verneuil L, Silvestre J, Mouchet F, Flahaut E, Boutonnet JC, Bourdiol F, Bortalomiol T, Baque D, Gauthier L, Pinelli E. 2015. Multi-walled carbon nanotubes, natural organic matter and the benthic diatom Nitzschia palea: “a sticky story”. Nanotoxicology. 9(2), 219-229.10.3109/17435390.2014.918202. http://dx.doi.org/10.3109/17435390.2014.918202.

23. Bour A, Mouchet F, Verneuil L, Evariste L, Silvestre J, Pinelli E, Gauthier L. 2015.Toxicity of CeO2 nanoparticles at different trophic levels - Effects on diatoms, chironomids and amphibians. Chemo. 120: 230-236. doi: 10.1016/j.chemosphere.2014.07.012

24. Bour A, Mouchet F, Silvestre J, Gauthier L, Pinelli E. 2015. Environmentally relevant approaches to assess nanoparticles ecotoxicity: a review. J. Hasard. Materials. 283:764-77. doi: 10.1016/j.jhazmat.2014.10.021.

25. Bourdiol F, Dubuc D, Grenier K, Mouchet F, Gauthier L, Flahaut E. 2015.Quantitative detection of carbon nanotubes in biological samples by an original method based on microwave permittivity measurements.  Carbon. 81: 535–545.10.1016/j.carbon.2014.09.086.

26. Verneuil L, Silvestre J, Randrianjatovo I, Romain-Marcato CE, Girbal-Neuhauser E, Mouchet F, Flahaut E, Gauthier L, Pinelli E. 2015. Double walled carbon nanotubes promote the overproduction of extracellular protein-like polymers inNitzschia palea: an adhesive response for an adaptive issue. Carbon. 113-125 10.1016/j.carbon.2015.02.053. 88: 113-125.

27. Mouchet F, Teaniniuraitemoana V, Baudrimont M, Daffe, Gauthier L, Gonzalez P. 2015. Recovery capabilities ofXenopus laevis after exposure to Cadmium and Zinc. Chemo 139: 117-125. doi: 10.1016/j.chemosphere.2015.05.103

28. Bour A, Mouchet F, Cadarsi S, Silvestre J, Verneuil L, Baque D, Chauvet E, Bonzom JM, Pagnout C, Clivot H, Fourquaux I, Tella M, Auffan M, Silvestre J, Gauthier L, Pinelli E. 2016. Toxicity of CeO2 nanoparticles on a freshwater experimental trophic chain: a study in environmentally relevant conditions through the use of mesocosms. Nanotoxicology 10(2): 245-255. doi: 10.3109/17435390.2015.1053422.

29. Mouchet F, Gancet C, Flahaut E, Pinelli E, Boutonnet JC, Gauthier L. 2016. International standardized procedures for in vivo evaluation of multi-walled carbon nanotube toxicity in water.  Toxicol Environ Chem. 98(8): 829-847. 10.1080/02772248.2015.1133818. http://dx.doi.org/10.1080/02772248.2015.1133818

30. Mottier A, Mouchet F, Laplanche C, Cadarsi S,  Lagier L, Arnault JC, Girard HA, Léon V, Vaszquez E, Sarrieu C, Pinelli E, Gauthier L, and Flahaut E. 2016. Surface area of carbon nanoparticles: a dose metric for a more realistic ecotoxicological assessment. Nano Lett.Am Chem S. 16(6): 3514-3518. 10.1021/acs.nanolett.6b00348

31. Muzi L, Mouchet F, Cadarsi S, Janowska I, Russier J, Ménard-Moyon C, Risuleo G, Soula B, Galibert AM, Flahaut E, Pinelli E, Gauthier L, Bianco A. 2016. Examining the impact of multi-layer graphene using cellular and amphibian models. 2D-Nanomat. 3(2):  10.1088/2053-1583/3/2/025009. http://dx.doi.org/10.1088/2053-1583/3/2/025009

32. Bour A, Mouchet F, Cadarsi S, Silvestre J, Chauvet E, Bonzom JM, Pagnout C, Clivot H, Gauthier L and Pinelli E. 2016. Impact of CeO2 nanoparticles on the functions of freshwater ecosystems: a microcosm study. Environ. Sci.: Nano, 3: 830-838. DOI: 10.1039/C6EN00116E.

33. Garacci M, Barret M, Mouchet F, Sarrieu C, Lonchambon P, Flahaut, Gauthier L, Silvestre J, Pinneli E. 2017. Few Layer Graphene sticking by biofilm of freshwater diatom Nitzschia palea as a mitigation to its ecotoxicity. Carbon. 113: 139-150. http://dx.doi.org/10.1016/j.carbon.2016.11.033.

 34. Mottier A, Mouchet F, Pinelli E, Gauthier L, Flahaut E. 2017. Environmental impact of engineered carbon nanoparticles: from releases to effects on the aquatic biota.  Current Opt. Biotechnol. 46: 1-6. http://dx.doi.org/10.1016/j.copbio.2016.11.024

35. Lagier L, Mouchet F, Laplanche C, Mottier A, Cadarsi S, Evariste L, Sarrieu C, Lonchambon P, Pinelli E, Flahaut E, Gauthier L. 2017. Surface area of carbon-based nanoparticles prevails on dispersion for growth inhibition in amphibians. Carbon 119: 72-81. https://doi.org/10.1016/j.carbon.2017.04.016

36. Bour A, Mouchet F, Cadarsi S, Silvestre J, Baqué D, Gauthier L, Pinelli E. 2017. CeO2 nanoparticles fate in environmental conditions and toxicity on a freshwater predator species: a microcosm study.Environ Sci Pollut Res Int. doi: 10.1007/s11356-017-9346-1.

37. Bengt F, Bussy C, Merino S,  Vázquez E, Flahaut E, Mouchet F, Evariste L, Gauthier L, Koivisto J, Vogel U, Martín C, Delogu LG, Buerki-Thurnherr T, Wick P, Beloin-Saint-Pierre D, Hischier R, Pelin M, Candotto Carniel F, Tretiach M, Cesca F, Benfenati F, Scaini D, Ballerini L, Kostarelos K, Prato M, and Bianco A.2018. Disentangling structure-activity relationships for graphene-based materials. ACS Nano. 12(11): 10582–10620. DOI: 10.1021/acsnano.8b04758.

38. Vijayaraj V, Liné C, Cadarsi S, Salvagnac C, Baqué D, Elger A, Barret M, Mouchet F, Larue C. 2018. Transfer and Ecotoxicity of Titanium Dioxide Nanoparticles in the Terrestrial and Aquatic Ecosystems: A Microcosm Study. Environ. Sci. Technol., 52 (21), pp 12757–12764 DOI: 10.1021/acs.est.8b02970.

39. Evariste L, Mouchet F, Pinelli E, Mottier A, Gauthier L, Baret M.2018. Gut Microbiota of Aquatic Organisms: A key endpoint for ecotoxicological studies. Env. Pollut. 248: 989-999.

40. Evariste L, Lagier L, Gonzalez P, Mottier A, Mouchet F, Cadarsi S, Lonchambon P,  Daffe G, Chimowa G, Sarrieu C, Ompraret E, Galibert AM, Ghimbeu CM, Pinelli E, Flahaut E and Gauthier L.2018. Thermal reduction of Graphene Oxide mitigates itsin vivo genotoxicity towardXenopus laevistadpoles. Nanomaterials. 9, 584-600; doi:10.3390/nano9040584.

41. Evariste L, Mottier A, Lagier L, Cadarsi S, Barret M, Sarrieu C, Soula B, Mouchet F, Flahaut E, Pinelli E and Gauthier L. 2019. Assessment of graphene oxide ecotoxicity at several trophic levels using aquatic microcosms. Carbon, 156: 261-271. https://doi.org/10.1016/j.carbon.2019.09.051

Publications dans des revues nationales à comité de lecture

1. Mouchet F, Denys S, Douay F, Pinet C, Marot F, Dumat C. 2008. Evaluation de la contamination de plantes potagères cultivées dans un environnement potentiellement pollué : contexte actuel et propositions d’outils opérationnels (Evaluation of the contamination of vegetables cultivated in a potentially polluted environment: current context and propositions of operational tools). Env Risques & Santé, mai-juin 2008, 7(3): 203-208. doi: 10.1684/ers.2008.0151.

2. Mouchet F, Landois P, Pinelli E, Flahaut E, Gauthier L. 2009. Ecotoxicité des  nanotubes de carbone dans l’environnement : contexte et état de l’art. (Carbon nanotubes in the environment and their potential ecotoxicity: Context and state of the art). Env Risques & Santé, janvier-février 2009, 8(1): 47-55. doi: 10.1684/ers.2009.0215

3.Coutand M, Mouchet F, Cyr M, Gauthier L, Clastres P. 2010. Ecotoxic evaluation of mortar leachate using the amphibian larvae (Xenopus laevis), Déchets sciences et techniques, N°57, 2010, p. 12.

4. Mouchet F, Flahaut E, Pinelli E, Gauthier L. 2013. Nanotubes de Carbone : quels risques pour l’environnement ? Biofutur. Vol.32 n°347, Octobre 2013. Synthèse et Caractérisation. Nanotoxicologie. De l’organisme à l’écosystème. Pp: 29-33.   http://biofutur.revuesonline.com/resnum.jsp?editionId=1760

5. Flahaut E, Evariste L, Gauthier L, Larue C, Line C, Meunier E, Mouchet F. 2018.Toxicité des nanotubes de carbone envers l’homme et l’environnement (Toxicity of Carbon Nanotubes towards Human and the Environment). Techniques de l’Ingénieur, octobre 2018.

Chapitres de livre

1. Gauthier L, Mouchet F. 2007. Utilisation de larves d’amphibiens pour évaluer le pouvoir génotoxique d’effluents autoroutiers. Autoroutes et aménagement. Interactions avec l’environnement. Collection Gérer l’environnement. Presses Polytechniques et Universitaires Romandes.

2. Auffan M, Flahaut E, Thill A, Mouchet F, Carriere M, Gauthier L, Achouak W, Rose J, Wiesner M, Bottero JY. 2010. Ecotoxicologie : réactivité des nanoparticules vis-à-vis des organismes vivants. Chapitre 14 de l’ouvrage: Les NANOSCIENCES, Tome 4: Nanotoxicologie et  nanoéthique, collection Echelles, Edts BELIN. 608 p. ISBN 978-2-7011-5593-7.Trophée Roberval, grand prix spécial du jury, Nov. 2011.

3. Auffan M, Flahaut E, Thill A, Mouchet F, Carriere M, Gauthier L, Achouak W, Rose J, Wiesner M, Bottero JY. 2011. Ecotoxicology : nanoparticle reactivity and living organisms. In Nanoethics & Nanotoxicology, Vol. 4, P. Houdy, M. Lahmani and F. Marano Editors, SPRINGER Edts, 620 p. ISBN 978-3-642-20176-9, DOI 10.1007/978-3-642-20177-6, e-ISBN 978-3-642-20177-6.Parution anglaise de l’ouvrage “Nanosciences”.

4. Mouchet F, Landois P, Bourdiol F, Fourquaux I, Puech P, Flahaut E, Gauthier L. 2012. Ecotoxicology of carbon nanotubes toward amphibian larvae. In Encyclopedia of Nanotechnology. Springer editor. Pp. 637-645. Bhushan Barat Eds, SPRINGER Reference publishers, 2868 p. ISBN 978-90-481-9752-1

5. Mouchet F, Gauthier L. 2013. Genotoxicity of contaminants: amphibian micronucleus assay.  In Encyclopedia of Aquatic Toxicology. Comprehensive Handbook (or Practical Guide) of ecotoxicological terms  (C. Blaise and JF. Férard editors). Springer Publishers, Dordrecht, The Netherlands. 1221 p, 2 vol. ISBN 978-94-007-5040-1 (Print), 978-94-007-5704-2 (on line).

6. Gauthier L and Mouchet F. 2016. Genotoxicity in urodele amphibians Pleurodeles waltl and Ambystoma mexicanum (Lissamphibia, Caudata) exposed to freshwater pollutants: a historical view. In Ecotoxicology and Genotoxicology: Non-traditional Aquatic Models, Issues in Toxicology. Chapt A23. Royal Society of Chemistry, Cambridge, UK,  Ed. Marcelo L. Larramendy.

I-CEINT (2010-2018) : International Consortium for Environmental Implications of Nano Technologies, Groupement de Recherche International (GDR-I), Impact des nanomatériaux sur l’environnement, évaluation des risques. 9 laboratoires français (CEA/CNRS/Universités) et 3 Universités américaines (Duke, Carnegie Mellon, Kentuky), Coordinateur J.Y. Bottero (CEREGE)

MESONNET (2010-2015) : Utilisation de mésocosmes terrestres et aquatiques en réseau pour l'évaluation du risque associé à la dispersion de nanoparticules manufacturées, ANR P2N nanotechnologies & nanosystèmes, 5 laboratoires CNRS (LHYGES, LIEBE, ECOLAB, CINAM, IN-FAME),3 CEA (Saclay, Liten, Fontenay-aux – roses), Universités Aix-Marseille, Toulouse, Paris VI. Coordinateur J.Y. Bottero (CEREGE)

DECANO (2011 – 2015) : Dégradation bactérienne et impact environnemental des nanotubes de carbone, ANR CESA, Laboratoires CNRS LEMIRE, Institut Biologie Moléculaire de Strasbourg, CEA Saclay, IRSN Cadarache et Université Paul Sabatier Toulouse III (ECOLAB et CIRIMAT), Coordinateur A. Bianco (IBM)

ELISE (2012 – 2014) : Evaluation in situ de l’impact des produits phytosanitaires sur les eaux souterraines et les écosystèmes associés de la plaine alluviale de l’Ariège, BRGM/FEDER, 7 Laboratoires nationaux partenaires avec le BRGM, Coordinateur N. Baran (BRGM)

GRAPHENE FLAGSHIP Ram Up Phase (2013 – 2016) : Graphene and Human Brain Project, Implication dans le WP Health & Environment, Europe FP7, Coordinateur Chalmers University of Technology, Gothenburg, Sweden, responsable scientifique ECOLAB L. Gauthier

SMS (2014 – 2018) : Séparation des Micropolluants à la Source, programme DEB – ONEMA – Agences de l’Eau 2013, Innovations et Changements de pratiques : Lutte contre les micropolluants des eaux urbaines, Coordinateur M. Vollo (Dir. général des services de la Ville de Portet-sur-Garonne)

TESTRAP (2014 – 2018) : Evaluation Technique et Environnementale d’un Système de TRAitement Physico chimique autonome des eaux, Projet FEDER-FSE,  AO AP ISINOV-ECO INNOV  avec un industriel (RPI Ramonville productique), Partenariat LGC/ECOLAB. Coordinateur F. Mouchet (ECOLAB) & P.Destrac (LGC)

TEESUFE (2015 – 2017) : Evaluation Technique, Economique environnementale et sociétale d’une filière innovante de traitement d’effluents à base de ferrates de potassium, Contrat d’appui PME INNOVATION de la région Occitanie, Coordinateur  E. Pinelli & F.Mouchet (ECOLAB)

GRAPHENE FLAGSHIP CORE1 (2016-2018), Europe H2020, Implication dans le WP2 Health & Environment, Coordinateur Chalmers University of Technology, Gothenburg, Sweden, Responsable scientifique ECOLAB L. Gauthier

GRAPHENE FLAGSHIP CORE2 (2018 – 2020), Europe H2020, Implication dans le WP4 Health & Environment, Coordinateur: Chalmers University of Technology, Gothenburg, Sweden, Responsable scientifique ECOLAB L. Gauthier

EMPEC (2017-2019) : Evaluation Ecotoxicologique des Micro- et nano- Plastiques des Eaux Continentales, Programme National de Recherche Environnement – Santé – Travail / ANSES, Resp. L. Gauthier , 3 laboratoires français (IMRCP, ECOLAB, GéoSciences Rennes)

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